Which of the following progesterone is used in emergency contraception ?
**Core Concept**
Progesterone and progestins are crucial in emergency contraception, as they prevent ovulation, fertilization, or implantation of the fertilized egg. The correct choice of progesterone is essential in emergency contraception.
**Why the Correct Answer is Right**
Ulipristal acetate (UPA) is a selective progesterone receptor modulator (SPRM) that is used in emergency contraception. It works by inhibiting the action of progesterone on the uterus, thereby preventing implantation of the fertilized egg. UPA also has a weak anti-estrogenic effect, which may contribute to its contraceptive efficacy.
**Why Each Wrong Option is Incorrect**
**Option A:** Levonorgestrel is a progestin used in combination with estrogen in combined oral contraceptives, but it is not typically used as a standalone agent in emergency contraception. While it has some efficacy in preventing ovulation, it is less effective than ulipristal acetate.
**Option B:** Medroxyprogesterone acetate is a long-acting progestin used in injectable contraceptives, but it is not used in emergency contraception.
**Option C:** Norethindrone is a progestin used in some oral contraceptives, but it is not typically used in emergency contraception.
**Option D:** This option is blank, as the question text was incomplete.
**Clinical Pearl / High-Yield Fact**
Ulipristal acetate (UPA) has a longer window of use compared to levonorgestrel, allowing it to be used up to 120 hours (5 days) after unprotected sex, whereas levonorgestrel is most effective when used within 72 hours.
**Correct Answer:** C.