ELISA is performed on a population with low prevalence, What would be the result of performing double screening ELISA tests-

A. Increased sensitivity and positive predictive value

B. Increased sensitivity and negative predictive value

C. Increased specificity and positive predictive value

D. Increased specificity and negative predictive value

Correct Answer: Increased specificity and positive predictive value

Description: Ref: Parks 23rd edition pg 139 Double ELISA meaning screening test is done in series. Series screening test : Sensitivity decreases Specificity increases PPV increases NPV decreases

Category: Social & Preventive Medicine

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