## Core Concept
Eclampsia is a severe complication of preeclampsia characterized by new-onset seizures in pregnant women. Treatment aims to control seizures, lower blood pressure, and prevent complications for both mother and neonate. The impact of eclampsia treatment on neonates varies depending on the therapeutic approach.
## Why the Correct Answer is Right
Magnesium sulfate (option ) is commonly used to prevent seizures in eclampsia. It has a relatively minimal direct effect on neonates when used appropriately, as it does not significantly depress neonatal respiratory or cardiovascular functions at therapeutic doses. In contrast, other antihypertensive or antiseizure medications may have more pronounced effects on the neonate.
## Why Each Wrong Option is Incorrect
* **Option A:** Antihypertensive medications like nifedipine or labetalol can affect uteroplacental blood flow and potentially cause fetal growth restriction or bradycardia, impacting the neonate.
* **Option B:** Diazepam crosses the placental barrier and can cause significant neonatal sedation and respiratory depression.
* **Option D:** Phenytoin can cause fetal cardiac arrhythmias and has teratogenic effects, impacting the neonate.
## Clinical Pearl / High-Yield Fact
A key point to remember is that magnesium sulfate is often considered the drug of choice for eclampsia prophylaxis and treatment due to its effectiveness and relatively favorable neonatal safety profile. However, careful monitoring of serum magnesium levels is crucial to prevent toxicity.
## Correct Answer: . Magnesium sulfate
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.