Medicine Earliest phenotypic manifestation of Idiopathic hereditary hemochromatosis is – A Post prandial increase in serum iron concentration B Elevated serum ferritin level C Slate grey pigmentation of skin D Increased transferrin saturation 💡 Explanation Earliest phenotypic manifestation of Idiopathic hereditary hemochromatosis is - ✓ Correct Answer: D. Increased transferrin saturation