Eale’s disease is best treated with
**Core Concept**
Eale's disease is a rare, idiopathic inflammatory condition characterized by recurrent episodes of retinal vasculitis, vitreous hemorrhage, and retinal neovascularization, leading to vision loss. The pathophysiology involves the formation of neovascularization, which is a response to ischemia in the retina.
**Why the Correct Answer is Right**
The treatment of Eale's disease primarily focuses on reducing inflammation, preventing neovascularization, and managing complications. **Pan-retinal photocoagulation (PRP)** is a laser treatment that targets areas of ischemic retina, reducing the stimulus for neovascularization. This is the treatment of choice for Eale's disease.
**Why Each Wrong Option is Incorrect**
**Option A:** Corticosteroids are used in the treatment of Eale's disease but are not the primary treatment. They are used to reduce inflammation and prevent complications.
**Option B:** Anti-vascular endothelial growth factor (VEGF) agents are used to treat various retinal disorders but are not the primary treatment for Eale's disease.
**Option C:** Vitrectomy is a surgical procedure that may be performed in cases of severe vitreous hemorrhage or retinal detachment but is not the primary treatment for Eale's disease.
**Clinical Pearl / High-Yield Fact**
Eale's disease is a rare condition that affects young adults, and its exact cause is still unknown. It is essential to diagnose and treat the condition promptly to prevent vision loss.
**Correct Answer: B. Pan-retinal photocoagulation (PRP) is the treatment of choice for Eale's disease.