Physiology Each hemoglobin contains A 2 polypeptide chains with 2 heme B 4 polypeptide chains with 2 heme C 2 polypeptide chains with 4 heme D 4 polypeptide chains with 4 heme 💡 Explanation Each hemoglobin contains ✓ Correct Answer: D. 4 polypeptide chains with 4 heme