Physiology During the metabolism of iodine in thyroid synthesis, Wolff-Chaikoff effect is seen due to: A Inhibition of cAMP response of TSH B Inhibition of proteolysis of Thyroglobulin C Inhibition of organic binding of iodide D Inhibition of iodide trapping mechanism 💡 Explanation During the metabolism of iodine in thyroid synthesis, Wolff-Chaikoff effect is seen due to: ✓ Correct Answer: C. Inhibition of organic binding of iodide