During an infection with Streptococcus pyogenes, an individual generated sufficiently high levels of IgM and IgG antibodies against Streptococcus pyogenes antigen with structural similarities to the heart that cardiac damage was caused. In this example the microbe contributed to autoimmunity via a process known as:
Correct Answer: Molecular mimicry
Description: Ans. (d)Molecular mimicry contribute to autoimmunity by triggering responses with microbial molecules that are cross reactive with host molecules. Anergy and central tolerance are mechanisms for preventing autoimmunity. Epitope spreading involves the generation of responses to a series with different antigens, not to cross reactive ones.
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now