Durg of choice in Delirium tremens is
**Core Concept**
Delirium tremens is a severe form of alcohol withdrawal that involves sudden and severe mental or nervous system changes. It is characterized by sudden onset of agitation, confusion, hallucinations, and altered sensorium. The treatment of choice involves medications that help manage symptoms and prevent seizures.
**Why the Correct Answer is Right**
The benzodiazepines are the preferred treatment for delirium tremens due to their efficacy in reducing the severity of symptoms and preventing seizures. They work by enhancing the activity of the neurotransmitter GABA (gamma-aminobutyric acid) in the brain, which has a calming effect on the nervous system. Lorazepam is a commonly used benzodiazepine for this purpose due to its rapid onset of action and ability to be titrated easily.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because barbiturates are not typically used to treat delirium tremens due to their potential for causing respiratory depression and other adverse effects.
**Option B:** This option is incorrect because antipsychotics are not the primary treatment for delirium tremens and may even worsen symptoms in some cases.
**Option C:** This option is incorrect because anticonvulsants may be used to prevent seizures in delirium tremens, but they are not the primary treatment for the condition.
**Clinical Pearl / High-Yield Fact**
It's essential to note that benzodiazepines should be used with caution in patients with a history of substance abuse, as they can be abused themselves. Additionally, patients with delirium tremens should be closely monitored for signs of withdrawal and seizures.
**Correct Answer: D. Lorazepam**