Drugs used in the treatment of obesity in a 36 year old man is/are which of the following?
Correct Answer: All of the above
Description: Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. It is intended for use in conjunction with a physician-supervised reduced-calorie diet. Sibutramine is a centrally-acting serotonin-nor epinephrine reuptake inhibitor, structurally related to amphetamines. It reduces the reuptake of serotonin, nor epinephrine, and dopamine, thereby increasing the levels of these substances in synaptic clefts and helping enhance satiety. Rimonabant is an anorectic antiobesity drug that has been withdrawn from the market. It is an inverse agonist for the cannabinoid receptor CB1. Its main effect is reduction in appetite.
Category:
Pharmacology
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