Drugs used in chronic hea failure all except
Correct Answer: Isosorbide nitrate
Description: Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no:166 Aldosterone antagonist (spironolactone, eplerenone) These medicines prevent your body from producing too much of the hormone aldosterone that can damage your hea. Common side effects of aldosterone antagonists: Changes in kidney function Hydralazine and nitrates (Apresoline, Nitrobid, Imdur, Isordil) Hydralazine and nitrates are often used together to treat hea failure. They dilate blood vessels so it's easier for your hea to receive and pump blood. Common side effects of hydralazine and nitrates: Dizziness Headache Digoxin (Lanoxin) This medicine slows hea rate and might improve the pumping ability of your hea. You'll get a blood test to make sure the dose you're taking is right for you. Common side effects of digoxin: Nausea Poor appetite Diuretics: furosemide (Lasix), bumetanide (Bumex), torsemide (Demadex), metolazone (Zaroxolyn) These medicines are called water pills because they remove excess fluid from the body to help you breathe easier and feel better. If you take a diuretic once a day, take it in the morning. If you take it twice a day, try to take the second dose no later than 4 p.m. to lessen the urge of going to the bathroom during the night. If you take metolazone plus another diuretic, take metolazone first, about 30 minutes before the other diuretic. ACE inhibitors (lisinopril, captopril) Angiotensin conveing enzyme (ACE) inhibitors reduce the amount of hea-damaging hormones your body produces. They also dilate blood vessels and lower blood pressure to lessen the workload of your hea. Common side effects of ACE inhibitors: Dizziness Changes in kidney function Beta blockers (carvedilol, metoprolol, bisoprilol) These medicines lower hea rate and blood pressure, and protect your hea from ceain substances that can damage your hea. Beta blockers are often staed at a very low dose and then are increased until a dose is reached that works best. Ref Davidson 23rd edition pg 467
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