## Core Concept
The treatment of migraine involves various classes of drugs, including triptans, ergots, anti-nausea medications, and preventive medications. The goal is to alleviate symptoms and prevent future attacks. **Serotonin receptors**, particularly 5-HT1B and 5-HT1D receptors, play a crucial role in the pathophysiology and treatment of migraine.

## Why the Correct Answer is Right
The correct answer, **Sumatriptan**, is a selective serotonin receptor agonist, specifically targeting 5-HT1B and 5-HT1D receptors. By activating these receptors, sumatriptan causes vasoconstriction of intracranial blood vessels and inhibits the release of pro-inflammatory neuropeptides, which are involved in the migraine process. This results in the alleviation of migraine headache.

## Why Each Wrong Option is Incorrect
* **Option A:** Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief but is not specific for migraine treatment and can have gastrointestinal side effects.
* **Option B:** Propranolol is a beta-blocker used as a preventive medication for migraine but is not used for acute attack treatment.
* **Option D:** Gabapentin is an anticonvulsant sometimes used for migraine prevention but not for the acute treatment of migraine.

## Clinical Pearl / High-Yield Fact
A key point to remember is that **triptans**, like sumatriptan, are effective for the acute treatment of migraine but should not be used more than 10 days per month to avoid medication-overuse headache.

## Correct Answer: C. Sumatriptan