**Core Concept**
Acute gout is a painful condition characterized by sudden onset of joint inflammation, primarily affecting the metatarsophalangeal joint of the big toe. It is caused by deposition of monosodium urate crystals, leading to activation of the inflammatory cascade.

**Why the Correct Answer is Right**
The treatment of choice for acute gout is nonsteroidal anti-inflammatory drugs (NSAIDs) or colchicine, which help reduce inflammation and alleviate pain. Colchicine works by inhibiting microtubule polymerization, thereby reducing the migration of neutrophils into the affected joint and subsequent inflammation. It also has a mild anti-inflammatory effect.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because corticosteroids are not the first-line treatment for acute gout. While they can be used in some cases, they are generally reserved for patients who are intolerant to NSAIDs or colchicine.
**Option B:** This option is incorrect because allopurinol is a xanthine oxidase inhibitor used to prevent gout attacks by reducing uric acid production. It is not used to treat acute gout attacks.
**Option C:** This option is incorrect because indomethacin is an NSAID that can be used to treat acute gout, but it is not the most commonly used or preferred option.

**Clinical Pearl / High-Yield Fact**
Remember that NSAIDs should be used with caution in patients with a history of peptic ulcers or kidney disease, and alternative treatments such as colchicine should be considered.

**Correct Answer: C. Indomethacin**