Drug used for sympathectomy in experimental animals is –
Correct Answer: Guanethidine
Description: Ans. is 'a' i.e., Guanethidine o Guanethidine is used for experimental sympthectomy.o Guanethidine a polar guanidine compound which is taken up into adrenergic nerve endings by active amine transport and has three important facets of action :Displaces NA from storage granules stochiometrically.Inhibits nerve impulse coupled release of NAEngages and blocks NA uptake mechanism at the axonal membrane,o It was used for sympathectomy in experimental animal.
Category:
Pharmacology
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