Drug used for cigarette smoking cessation?
Correct Answer: All of the above
Description: Ans. is 'd' i.e., All of the above Varenioline* It is a NR (Nicotine receptor) selective partial agonist and exerts rewarding action of nicotine through a4 b2 receptors.* This NN subtype nicotinic receptor partial agonist is under clinical trial for smoking cessation.Bupropion* This atypical antidepressants.* It inhibits DA and NA uptake.* It is metabolised to amphetamine like compound.* It is the only antidepressant which has excitatory action (all other have sedative action) can cause insomnia and can precipitate seizure.* It can be used in nicotine withdrawl for smoking cessation.Mecamylamine* It is nicotine ganglion blocker, blocks the reward effect of nicotine and abstinence.* Mecamylamine is used for smoking cessation.
Category:
Pharmacology
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