Drug that can cause complete histopathological resolution in patients with hepatitis B is:
Correct Answer: Entercavir
Description: ANTIVIRAL DRUGS: CLASSI FICATION Anti-Herpes virus Idoxuridine, Acyclovir, Valacyclovir, Famciclovir, Ganciclovir*, Foscarnet* 2 Anti-Retrovirus (a) Nucleoside reverse transcriptase inhibitors (Nis): Zidovudine (AZT), Didanosine, Zalcitabine*, Stavudine, Lamivudine, Abaca vir (b) Nonnucleoside reverse transcriptase inhibitors (NNis): Nevirapine, Eirenz, Delavirdine* (c) Protease inhibitors: Ritonavir, Indinavir, Nelfinavir, Saquinavir, Amprenavir*, Lopinavir 3. Anti-Influenza virus Amantadine, Rimantadine* 4. NonselectiVe antiviral drugs Ribavirin, Lamivudine, Adefovir dipivoxil, Interferon a * Not yet marketed in India. Entecavir is used to treat chronic (long-term) hepatitis B infection (swelling of the liver caused by a virus) in people who have liver damage. Entecavir is in a class of medications called nucleoside analogs. It works by decreasing the amount of hepatitis B virus (HBV) in the body. Entecavir does not cure HBV and may not prevent complications of chronic hepatitis B such as cirrhosis of the liver or liver cancer. Entecavir does not prevent the spread of HBV to other people. Calcineurin inhibitors (Specific T-cell inhibitors)(immunosuppressant drugs):cyclosporine It profoundly and selectively inhibits T lymphocyte proliferation, IL-2 and other cytokine production and response of inducer T cells to IL-l, without any effect on suppressor T-cells. Lymphocytes are arrested in G0 or G1 phase ESSENTIALS OF MEDICAL PHARMACOLOGY,medlineplus.gov/druginfo/meds/a605028.html K.D.TRIPATHI SIXTH EDITION PAGE NO:837,767 .
Category:
Pharmacology
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