Drug of choice in sarcoidosis is
**Core Concept**
Sarcoidosis is a systemic granulomatous disease characterized by the formation of non-caseating granulomas in various organs, particularly the lungs and lymph nodes. The disease can cause a range of symptoms, including respiratory problems, skin lesions, and eye inflammation. In some cases, sarcoidosis can lead to organ damage and require treatment with immunosuppressive medications.
**Why the Correct Answer is Right**
The drug of choice in sarcoidosis is corticosteroids, specifically prednisone. Corticosteroids work by reducing inflammation and suppressing the immune system, which helps to alleviate symptoms and prevent further organ damage. In severe cases of sarcoidosis, corticosteroids can be used to induce remission and prevent long-term damage to the lungs and other organs.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify a corticosteroid, which is the primary treatment for sarcoidosis.
**Option B:** This option is incorrect because it is a non-steroidal anti-inflammatory drug (NSAID), which is not effective in treating the underlying inflammation and immune response in sarcoidosis.
**Option C:** This option is incorrect because it is a biologic agent used to treat autoimmune diseases, but it is not the first-line treatment for sarcoidosis.
**Clinical Pearl / High-Yield Fact**
It's essential to note that corticosteroids can have significant side effects, particularly with long-term use, so treatment should be individualized and monitored closely.
**Correct Answer:** C.