Drug of choice in interstitial lung disease is
Correct Answer: Steroid
Description: Glucocoicoids are the mainstay of therapy for suppression of the alveolitis present in ILD.Glucocoicoid therapy is recommended for symptomatic ILD patients with eosinophilic pneumonias,sarcoidosis,hypersensitivity pneumonitis,acute inorganic dust exposures,acute radiation pneumonitis,drug-induced ILD.In organic dust disease,glucocoicoids are recommended for both the acute and chronic stages.A common staing dose of steroid is prednisone,0.5-1 mg/kg in a once-daily oral dose.This dose is continued for 4-12 weeks,at which time the patient is reevaluated.If the patient is stable or improved,the dose is tapered to 0.25-0.5 mg/kg and is maintained at this level for an additional 4-12 weeks,depending on the course.If the patient's condition continues to decline on glucocoicoids,a second agent like cyclophosphamide,azathioprine,methotrexate,colchicine,pencillamine ,etc can be added, and the prednisolone dose is lowered to or maintained at 0.25 mg/kg per dose. Ref:Harrison's medicine-18th edition,page no:2164-2165.
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