Drug of choice in delirium tremens is –
**Core Concept**
The management of delirium tremens, a severe form of alcohol withdrawal, involves the use of medications that can effectively reduce symptoms and prevent complications. **Benzodiazepines** are a class of drugs commonly used in this context due to their sedative, anxiolytic, and anticonvulsant properties.
**Why the Correct Answer is Right**
The correct answer is a **benzodiazepine**, as these drugs are considered the first-line treatment for delirium tremens. They work by enhancing the effect of **gamma-aminobutyric acid (GABA)**, a neurotransmitter that inhibits neuronal activity, thereby reducing anxiety, insomnia, and seizure risk associated with alcohol withdrawal.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because, although other classes of drugs may be used as adjuncts, they are not the primary treatment for delirium tremens.
**Option B:** Incorrect as it is not the most appropriate choice for managing delirium tremens.
**Option D:** Incorrect because it is not typically used as a first-line treatment for this condition.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **diazepam** and **lorazepam** are often preferred benzodiazepines in this setting due to their pharmacokinetic profiles, which allow for flexible dosing and a lower risk of accumulation.
**Correct Answer:** D. Diazepam