**Core Concept**
The question requires knowledge of pharmacological management strategies for Alzheimer's disease, a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. The correct answer involves understanding the current evidence-based treatment options for this condition.

**Why the Correct Answer is Right**
The drug of choice for the treatment of Alzheimer's disease is Cholinesterase inhibitors, specifically donepezil (Aricept). These medications work by increasing the concentration of acetylcholine in the brain, a neurotransmitter that plays a key role in memory and learning. By inhibiting the enzyme acetylcholinesterase, which breaks down acetylcholine, these medications help to improve cognitive function and slow the progression of the disease.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect as Cholinesterase inhibitors are the primary treatment for Alzheimer's disease, not antipsychotics. Antipsychotics are used to manage behavioral symptoms such as agitation and aggression in Alzheimer's patients.
* **Option B:** This option is incorrect as Memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist, which is used as a second-line treatment for Alzheimer's disease, not as a first-line treatment. Cholinesterase inhibitors like donepezil are generally recommended first.
* **Option C:** This option is incorrect as there is no specific "drug of choice" for Alzheimer's disease among the options listed. While Cholinesterase inhibitors like donepezil are the primary treatment, the question asks for the "drug of choice," which implies a single best option.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that the primary treatment for Alzheimer's disease involves Cholinesterase inhibitors, and these medications should be initiated early in the course of the disease to maximize their effectiveness. Additionally, non-pharmacological interventions such as cognitive training and behavioral therapy should also be considered as part of a comprehensive treatment plan.

**Correct Answer:** C.