Drug of choice for treatment of acute asthmatic attacks is :
## **Core Concept**
The treatment of acute asthmatic attacks primarily involves bronchodilators to relax the smooth muscles around the airways, thereby improving airflow. The mainstay of therapy includes short-acting β2-adrenergic receptor agonists (SABAs) due to their rapid onset of action.
## **Why the Correct Answer is Right**
The correct answer, **Short-acting β2 agonist (e.g., salbutamol/albuterol)**, is the drug of choice for the treatment of acute asthmatic attacks because it acts quickly to dilate the bronchial tubes, providing rapid relief from asthma symptoms. These medications work by stimulating β2-adrenergic receptors in the lungs, which leads to bronchodilation. Their quick action and effectiveness make them ideal for acute relief.
## **Why Each Wrong Option is Incorrect**
- **Option A:** **Anticholinergics (e.g., ipratropium bromide)** can be used in asthma treatment, especially in combination with β2 agonists for additive benefit, but they are not the first line for acute asthma attacks due to their slower onset of action compared to SABAs.
- **Option B:** **Long-acting β2 agonists (LABAs)** are used for long-term control of asthma symptoms, not for acute relief, as they have a slower onset of action.
- **Option C:** **Corticosteroids** are crucial in the management of asthma for their anti-inflammatory effects but are not used for immediate relief of acute asthma attacks. They are more preventive than therapeutic in the acute setting.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is the use of a **peak flow meter** to assess the severity of an asthma attack and to monitor response to treatment. Also, in acute asthma, **salbutamol/albuterol** can be administered via a metered-dose inhaler (MDI) with a spacer or via a nebulizer, with the choice depending on the patient's condition and ability to use an MDI effectively.
## **Correct Answer:** . **Short-acting β2 agonist**