Drug of choice for the treatment of acute gout in patients in whom NSAIDs are contraindicated is?
Correct Answer: Colchicine
Description: Ans. is 'a' i.e., Colchicine Treatment of Gout 1) Acute gout NSAIDs are the drugs of choice Colchicine is the fastest acting drug. However it is reserved for the patients in which NSAIDs are contraindicated, because colchicine can cause gastrointestinal disturbances. If neither NSAIDs nor colchicin are tolerated, oral prednisolone is used. Allopurinol and uricosuric drugs (sulfinpyrazone, probenacid) are not effective in acute gout because they will not relieve symptoms as they don't have anti-inflammatory propey. 2) Chronic gout Allopurinal is the drug of choice. Other drugs are sulfinpyrazone and probenacid.
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