Drug of choice for rapid cyclers in manic-depressive psychosis is:
Correct Answer: Valproate
Description: uction in manic relapses is noted when valproate is used in bipolar disorder. It is now a first line treatment of acute mania in which high dose valproate acts faster and is an alternative to antipsychotic +- benzodiazepine. It can be useful in those not responding to lithium or not tolerating it. Patients with rapid cycling pattern may paicularly benefit from valproate therapy Ref: KD Tripati 8th ed.
Category:
Pharmacology
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