## **Core Concept**
Pregnancy-induced hypertension, also known as gestational hypertension or pregnancy-related hypertension, requires careful management to prevent complications for both the mother and the fetus. The management involves antihypertensive drugs that are safe for both the mother and the fetus.

## **Why the Correct Answer is Right**
Methyldopa (**Option C**) is considered the drug of choice for pregnancy-induced hypertension. It works centrally by stimulating α2-adrenergic receptors, which decreases the sympathetic tone, leading to decreased blood pressure. Methyldopa has a long history of safe use in pregnancy and is often considered the first-line treatment due to its efficacy and safety profile for both the mother and the fetus.

## **Why Each Wrong Option is Incorrect**
- **Option A:** Nifedipine, a calcium channel blocker, can be used in pregnancy-induced hypertension but is typically considered after methyldopa or in specific cases due to potential side effects like reflex tachycardia and more pronounced vasodilation effects.
- **Option B:** Propranolol, a beta-blocker, can be used but is generally avoided in the first trimester due to potential growth restriction and other complications. It's not the first choice for pregnancy-induced hypertension.
- **Option D:** Lisinopril, an ACE inhibitor, is contraindicated in pregnancy due to the risk of fetal harm, including effects on the renal system and potential for growth restriction.

## **Clinical Pearl / High-Yield Fact**
A key point to remember is that in managing pregnancy-induced hypertension, the goal is to balance the control of blood pressure with the safety of the fetus. Methyldopa has been used for decades and has a well-established safety profile, making it a preferred choice.

## **Correct Answer:** C. Methyldopa.