Drug of choice for paroxysmal supraventricular tachycardia is:
## **Core Concept**
Paroxysmal supraventricular tachycardia (PSVT) refers to a type of abnormal heart rhythm that originates above the ventricles, leading to a rapid heart rate. The management of PSVT often involves the use of medications that can help restore a normal heart rhythm or control the ventricular rate. The drugs of choice typically work by affecting the atrioventricular (AV) node.
## **Why the Correct Answer is Right**
The correct answer, Adenosine, is the drug of choice for PSVT because it works by transiently blocking conduction through the AV node, which can interrupt the re-entrant circuit that sustains the tachycardia. Adenosine has a very short half-life, which makes it ideal for acute management as it can quickly terminate the PSVT with minimal side effects. It acts rapidly and has a high efficacy rate for converting PSVT to a normal sinus rhythm.
## **Why Each Wrong Option is Incorrect**
- **Option A:** Although Atropine can be used in certain bradyarrhythmias and asystole, it is not the first-line treatment for PSVT. Atropine works by increasing heart rate through its anticholinergic effects but does not directly affect the re-entrant circuits in PSVT.
- **Option B:** Verapamil is a calcium channel blocker that can be used to treat PSVT by slowing AV nodal conduction. However, it is not the first-line treatment for acute management of PSVT due to its slower onset of action compared to Adenosine and potential for causing hypotension.
- **Option D:** Digoxin can be used for rate control in atrial fibrillation and flutter but is not the drug of choice for acute termination of PSVT due to its slower onset of action and narrower therapeutic window.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that Adenosine is administered as a rapid bolus injection followed by a saline flush. The classic presentation of Adenosine administration is a brief period of asystole or profound bradycardia before the heart rhythm returns to normal, which can be alarming but is generally not harmful.
## **Correct Answer:** . Adenosine