Drug of choice for intermediate uveitis –
**Core Concept**
Intermediate uveitis is a type of non-infectious uveitis characterized by inflammation of the middle layer of the eye, including the vitreous, retina, and choroid. The goal of treatment is to reduce inflammation and prevent complications such as retinal detachment.
**Why the Correct Answer is Right**
The drug of choice for intermediate uveitis is typically a corticosteroid, specifically triamcinolone acetonide (Kenalog), which is administered via intravitreal injection. This approach allows for high concentrations of the medication to be delivered directly to the site of inflammation, reducing the risk of systemic side effects. Corticosteroids work by inhibiting the synthesis of pro-inflammatory cytokines, thereby reducing inflammation.
**Why Each Wrong Option is Incorrect**
**Option A:**
This option is incorrect because while NSAIDs may be used to treat mild inflammatory conditions, they are not sufficient for managing intermediate uveitis, which requires more potent anti-inflammatory therapy.
**Option B:**
This option is incorrect because while antiviral medications may be indicated in certain cases of uveitis, they are not the primary treatment for intermediate uveitis, which is typically non-infectious in nature.
**Option C:**
This option is incorrect because while immunosuppressive agents may be used to treat severe or resistant cases of uveitis, they are not typically the first-line treatment for intermediate uveitis.
**Clinical Pearl / High-Yield Fact**
Corticosteroids are the mainstay of treatment for intermediate uveitis, and intravitreal injection allows for high concentrations of the medication to be delivered directly to the site of inflammation, reducing the risk of complications.
**Correct Answer: D. Triamcinolone acetonide (Kenalog) via intravitreal injection.**