Drug of choice for cutaneous larva migrans is ?
**Core Concept**
Cutaneous larva migrans (CLM) is a skin condition caused by the migration of larvae of certain nematodes, typically hookworms, through the skin. It is characterized by a serpiginous, itchy rash that can be painful and debilitating. The treatment of choice for CLM involves the use of antiparasitic medications that target the larvae.
**Why the Correct Answer is Right**
The drug of choice for cutaneous larva migrans is **ivermectin**. Ivermectin is a broad-spectrum antiparasitic medication that works by inhibiting the production of neurotransmitters in the parasite, leading to paralysis and death of the larvae. It is effective in treating CLM because it can penetrate the skin and reach the larvae, allowing for a rapid resolution of symptoms. Ivermectin is also well-tolerated and has a good safety profile, making it an ideal treatment option for this condition.
**Why Each Wrong Option is Incorrect**
**Option A:** **Metronidazole** is an antibiotic that is used to treat various bacterial and protozoal infections, but it is not effective against the larvae of nematodes and is not the treatment of choice for CLM.
**Option B:** **Corticosteroids** may be used to reduce inflammation and itching associated with CLM, but they do not target the underlying cause of the condition and are not a primary treatment option.
**Option C:** **Anthelmintics** such as albendazole may be used to treat certain parasitic infections, but they are not the first-line treatment for CLM and may not be as effective as ivermectin in this condition.
**Clinical Pearl / High-Yield Fact**
Ivermectin is also effective against other parasitic infections, including onchocerciasis and strongyloidiasis, and is often used in mass treatment campaigns to control these diseases in endemic areas.
**Correct Answer:** C. Ivermectin.