Drug of choice for anaerobic infection is
Correct Answer: Metronidazole
Description: Ans. is 'b' i.e., Metronidazole * Metronidazole is a prototype nitroimidazole which has broad spectrum cidal activity against the anaerobic micro-organisms including giardia lamblia.* It doesn't affect the aerobic bacteria.* It is selectively toxic to anaerobic and micro-aerophilic micro-organisms.* In anerobic conditions, it produces highly cytotoxic nitro radical which is attenuated in aerobic environment.* It also induces mutagenesis and cause radiosensitization.* Aminoglycosides are active only against aerobes.* Amphotericin B is an anti-fungal agent.
Category:
Pharmacology
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