Drug of choice for acute iridocyclitis is –
## **Core Concept**
Acute iridocyclitis, also known as anterior uveitis, is an inflammatory condition affecting the uveal tract of the eye, specifically the iris and ciliary body. The management of acute iridocyclitis involves the use of anti-inflammatory agents to reduce inflammation and prevent complications. Corticosteroids are a mainstay in the treatment due to their potent anti-inflammatory effects.
## **Why the Correct Answer is Right**
The correct answer, **D. Corticosteroids**, is the drug of choice for acute iridocyclitis because corticosteroids effectively reduce inflammation in the eye. They can be administered topically (as eye drops), periocularly (as injections around the eye), or systemically (orally or intravenously), depending on the severity of the condition. Corticosteroids work by inhibiting the production of pro-inflammatory cytokines and mediators, thereby reducing inflammation and preventing tissue damage.
## **Why Each Wrong Option is Incorrect**
- **Option A:** NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) can be used to treat mild cases of iridocyclitis or as adjunct therapy with corticosteroids but are not the primary treatment for acute iridocyclitis due to their less potent anti-inflammatory effects compared to corticosteroids.
- **Option B:** Antibiotics are used when there is a clear evidence of bacterial infection, which is not the case in typical acute iridocyclitis, making them not the drug of choice.
- **Option C:** Antiviral drugs are indicated for viral infections and are not typically used as a first-line treatment for acute iridocyclitis unless a viral etiology is suspected or confirmed.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that while corticosteroids are effective in treating inflammation in iridocyclitis, their long-term use can lead to complications such as cataract formation and increased intraocular pressure. Therefore, their use should be monitored closely by an ophthalmologist.
## **Correct Answer:** D. Corticosteroids.