Drug of choice for acute iridocyclitis is-
**Core Concept**
Acute iridocyclitis is an inflammatory condition of the iris and ciliary body, often caused by uveitis. The treatment involves anti-inflammatory and immunosuppressive medications to reduce inflammation and prevent further damage to the eye. The drug of choice should effectively reduce inflammation while minimizing side effects.
**Why the Correct Answer is Right**
The drug of choice for acute iridocyclitis is usually a corticosteroid, such as prednisolone. Corticosteroids work by suppressing the immune response and reducing inflammation in the eye. They can be administered topically (eye drops) or systemically (oral tablets). The mechanism of action involves the inhibition of phospholipase A2, leading to decreased production of pro-inflammatory mediators such as prostaglandins and leukotrienes.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is not a commonly used medication for treating iridocyclitis.
**Option B:** This option is incorrect because it is a non-steroidal anti-inflammatory drug (NSAID), which may exacerbate the condition by inducing prostaglandin production.
**Option C:** This option is incorrect because it is an antibiotic, which is not effective against the underlying inflammatory cause of iridocyclitis.
**Clinical Pearl / High-Yield Fact**
Corticosteroids can cause increased intraocular pressure (IOP) as a side effect, so patients with glaucoma should be monitored closely when treated with these medications.
**Correct Answer: C. Prednisolone**