Drug of choice for acute adrenal insufficiency is?
**Core Concept**
Acute adrenal insufficiency, also known as adrenal crisis, is a life-threatening condition that requires immediate medical attention. It occurs when the adrenal glands are unable to produce sufficient cortisol and aldosterone, leading to a severe imbalance in electrolytes and fluid status.
**Why the Correct Answer is Right**
The drug of choice for acute adrenal insufficiency is hydrocortisone, a synthetic glucocorticoid that mimics the action of cortisol. Hydrocortisone has both glucocorticoid and mineralocorticoid effects, making it an ideal choice for treating adrenal crisis. It helps to replace the deficient cortisol and aldosterone, thereby correcting the electrolyte and fluid imbalance.
**Why Each Wrong Option is Incorrect**
**Option A:** (Not provided)
**Option B:** (Not provided)
**Option C:** (Not provided)
**Option D:** (Not provided)
**Clinical Pearl / High-Yield Fact**
In cases of suspected adrenal crisis, it's essential to administer hydrocortisone promptly, even before laboratory confirmation of adrenal insufficiency. This is because the condition can be fatal if left untreated. Always remember the "4 Cs" of adrenal crisis management: Cortisol replacement, Correction of fluid and electrolyte imbalance, Control of blood pressure, and Correction of underlying cause.
**Correct Answer:** C. Hydrocortisone