Drug of choice for Acute Adrenal Crisis is:
Correct Answer: Hydrocoisone
Description: Answer is B (Hydrocoisone): The treatment of choice for acute adrenal insufficiency is Glucocoicoid Replacement Therapy. Hydrocoisone is the preferred steroid fir Glucocoicoid replacement therapy in acute adrenal crisis since it has both glucocoicoid and mineralocoicoid actions. In cases where the diagnosis of acute adrenal insufficiency is suspected (not confirmed) Dexamethasone is preferred as the initial steroid of choice because Dexamethasone does not compete with the coisol assay. 'Glucocoicoid replacement should be initiated by bolus injection of 100 mg Hydrocoisone, followed by the administration of 100-200mg hydrocoisone over 24 hours either by continuous infusion or provided by several IV or IM Injections. Mineralocoicoid replacement can be initiated once the daily hydrocoisone dose has been reduced to less than 50 mg because at higher doses hydrocoisone provides sufficient stimulation of glucocoicoid receptors'
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