Drug implicated in prolonging QT interval is:
Correct Answer: Cisapride
Description: Ans. (C) Cisapride(Ref: KDT 8th/e p715)Cisapride is a 5HT4 agonist that is useful as a prokinetic agent. At high plasma concentration, it can block cardiac K+ channels leading to polymorphic ventricular tachycardia (torsades de pointes). It is manifested in the ECG as QT prolongation. Therefore, cisapride should not be combined with microsomal enzyme inhibitors like erythromycin and ketoconazole. Other important drugs causing QT prolongation areTerfenadineAstemizoleZiprasidone
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now