Drug causing peptic ulcer are all except: (PGI Nov 2009)
**Core Concept**
The question tests the student's knowledge of pharmacological agents that can cause peptic ulcers, highlighting the importance of understanding drug side effects. **Nonsteroidal anti-inflammatory drugs (NSAIDs)** and **steroids** are well-known culprits.
**Why the Correct Answer is Right**
Since the correct answer isn't explicitly provided, let's assume a common exception: **misoprostol**, a synthetic prostaglandin analogue, which actually protects against peptic ulcers by replacing the protective prostaglandins that are inhibited by NSAIDs.
**Why Each Wrong Option is Incorrect**
**Option A:** If this were an NSAID, it would be incorrect because NSAIDs are known to cause peptic ulcers by inhibiting **cyclooxygenase (COX) enzymes**, reducing protective prostaglandins in the stomach lining.
**Option B:** If this were a steroid, it would be incorrect because steroids can increase the risk of peptic ulcers, possibly by enhancing the harmful effects of gastric acid.
**Option D:** Without the specific option details, we can speculate that any drug known to cause peptic ulcers would be an incorrect choice.
**Clinical Pearl / High-Yield Fact**
Remember, **proton pump inhibitors (PPIs)** and **H2 receptor antagonists** can help prevent NSAID-induced ulcers, making them crucial in managing patients on long-term NSAID therapy.
**Correct Answer:** Unfortunately, without the answer choices, the correct answer cannot be provided.