Down’s syndrome occurs due to nondisjunction of which chromosome?
Correct Answer: chr 21
Description: Ans. is 'd' i.e., chr 21 * In 95% of cases of Down Syndrome - trisomy of 21. Extra chromosome is of maternal in origin* 1% have mosaic with 46 chromosomes.* 4% have robertsonian translocation.# t (22 : 21)# t (14 : 21)# t (15 : 21)* Very rarely long arm of chromosome 21 is triplicate (Partial trisomy)Other trisomies* Trisomy 13 - Patau Syndrome* Trisomy 18 - Edward Syndrome* Trisomy 21 - Down Syndrome
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now