Down’s syndrome most commonly occurs due to –
Correct Answer: Nondysjunction in maternal meiosis
Description: Ans. is 'b' i.e., Nondysjunction in maternal meiosis In trisomy 21, the additional number 21 chromosome is derived from the mother in 95% of cases. It is due to nondysjunction of 21st chromosome at the time of meiosis. In nondysjunction, chromosomal pair fails to separate in first meiotic division during gametogenesis.
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