Dose of streptokinase to be used in Ml is ?
**Core Concept:** Streptokinase is a fibrinolytic agent used for the treatment of acute ischemic stroke. It is a recombinant form of streptokinase, which is derived from Streptococcus bacteria. Its primary action is to degrade fibrin deposits and restore blood flow in occluded arteries.
**Why the Correct Answer is Right:** Streptokinase is used in the treatment of acute ischemic stroke because it is a fibrinolytic agent that helps in breaking down fibrin deposits and restoring blood flow in occluded arteries. The correct answer is **Streptokinase (SK)**, because it is the recombinant form of streptokinase derived from Streptococcus bacteria. SK is a well-established treatment option for acute ischemic stroke, as it effectively dissolves fibrin clots and improves blood flow in affected areas.
**Why Each Wrong Option is Incorrect:**
A. Streptokinase (SK) is indeed used for thrombolysis in stroke but the dose is typically not specified in milliliters (mL). Instead, the dose is determined based on the patient's weight and clinical condition. The focus should be on the dose calculation method rather than the unit of measurement.
B. Lidocaine is an antiarrhythmic agent used for treating cardiac arrhythmias and not thrombolysis in stroke. It is unrelated to the treatment of acute ischemic stroke.
C. Alteplase (tPA) is another fibrinolytic agent used for thrombolysis in acute ischemic stroke. However, the correct answer is not a specific dose but the method for calculating the dose based on the patient's weight and clinical condition.
D. The unit of measurement (mL) is incorrect for the dosage of thrombolytic agents in stroke treatment. The correct dosage is determined based on the patient's weight and clinical condition, not the unit of measurement.
**Clinical Pearl:** When calculating the dosage of thrombolytic agents like streptokinase (SK) for stroke treatment, consider the patient's weight and clinical condition. The unit of measurement (mL) is not relevant, as the focus should be on the appropriate dosage calculation method.