Anaesthesia Dose of local anesthetics for peripheral nerve block is decreased in patients with hypovolemia shock because- A Preferential perfusion of vital organs in shock predisposes more to local anesthetics toxicity B Drugs cannot be metabolized C Sensitivity of voltage gated channel increases in shock D Drug is not systemically absorbed to less require 💡 Explanation Dose of local anesthetics for peripheral nerve block is decreased in patients with hypovolemia shock because- ✓ Correct Answer: A. Preferential perfusion of vital organs in shock predisposes more to local anesthetics toxicity