Dosage of drug is determined by following except-
Correct Answer: Half life
Description: Ans. is 'None', but go with "b" as the best option here o Loading dose is governed by volume of distribution and volume of distribution is affected by lipid solubility.o Maintenance dose is governed by clearance (excretion) of drug and half life.o For one option go ahead for option b ie half life because :"Clearance is the most important factor for maintenance dose".------Katzung 10th/e - 44
Category:
Pharmacology
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