Donovanosis/granuloma venerum is caused by
## **Core Concept**
Donovanosis, also known as granuloma venereum, is a sexually transmitted infection caused by a specific type of bacteria. The disease is characterized by genital ulcers and is more common in tropical regions. The causative organism is a type of Gram-negative bacterium.
## **Why the Correct Answer is Right**
The correct answer, **Klebsiella granulomatis (formerly known as Calymmatobacterium granulomatis)**, is a Gram-negative bacterium that causes Donovanosis. This bacterium infects the genital area, leading to the formation of ulcers. The infection is usually acquired through sexual contact and is more prevalent in tropical areas. The organism is known for its characteristic Donovan bodies, which are seen within the cytoplasm of infected macrophages under microscopic examination.
## **Why Each Wrong Option is Incorrect**
- **Option A:** *Neisseria gonorrhoeae* is incorrect because it causes gonorrhea, a different sexually transmitted infection characterized by symptoms such as urethritis and cervicitis.
- **Option B:** *Haemophilus ducreyi* is incorrect because it causes chancroid, another sexually transmitted infection that presents with painful genital ulcers and lymphadenopathy.
- **Option D:** *Treponema pallidum* is incorrect because it causes syphilis, a sexually transmitted infection that can present in various stages, including a primary chancre, which is a painless ulcer.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that Donovanosis is often confused with other sexually transmitted infections like syphilis and chancroid due to the presence of genital ulcers. However, Donovanosis is more commonly associated with a painless, beefy-red ulcer without lymphadenopathy. The disease is effectively treated with antibiotics such as azithromycin or doxycycline.
## **Correct Answer:** .