**Core Concept**
H. pylori and Campylobacter species are both spiral-shaped, Gram-negative bacteria, but they exhibit distinct biochemical characteristics. The production of specific enzymes differentiates these bacteria, aiding in their identification and diagnosis.
**Why the Correct Answer is Right**
H. pylori produces high levels of urease, an enzyme that breaks down urea into ammonia and carbon dioxide. This characteristic is crucial for the bacterium's survival in the acidic environment of the stomach. The urease enzyme also helps H. pylori to colonize the gastric mucosa and contribute to the development of peptic ulcers. In contrast, Campylobacter species generally do not produce urease or produce it in minimal amounts.
**Why Each Wrong Option is Incorrect**
**Option A:** Oxidase production is not a distinguishing characteristic between H. pylori and Campylobacter species, as both are oxidase-positive. This enzyme is involved in the bacterial electron transport chain.
**Option B:** Catalase production is also not a distinguishing feature, as both H. pylori and Campylobacter species are catalase-positive. This enzyme helps to decompose hydrogen peroxide into water and oxygen, protecting the bacteria from oxidative damage.
**Option D:** The curved shape of H. pylori and Campylobacter species is a morphological characteristic, not a biochemical or enzymatic one. Both bacteria exhibit a similar spiral shape, making this feature inconsequential for differentiation.
**Clinical Pearl / High-Yield Fact**
Urease testing is a valuable diagnostic tool for identifying H. pylori infections. A positive urease test can be used to confirm the presence of H. pylori in gastric biopsy samples or to detect the bacterium in stool or breath samples.
β Correct Answer: C. Urease production
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.