**Core Concept**
Infants with refusal to feed, vomiting, and abdominal distension in the first few days of life often present with a condition known as Congenital Hypoglycemia or Congenital Hyperinsulinism, which can be associated with various metabolic derangements. One common finding in these patients is the presence of reducing sugars in the urine, indicating an abnormal metabolic pathway.
**Why the Correct Answer is Right**
The urine Benedict's test is positive in this neonate, indicating the presence of reducing sugars. In Congenital Hypoglycemia, the body produces excess insulin, leading to increased glucose uptake by tissues and potentially resulting in the breakdown of glycogen to glucose. This glucose can then be converted to other sugars, such as lactose or galactose, which are reducing sugars. The most common reducing sugar found in the urine of these patients is Galactose.
**Why Each Wrong Option is Incorrect**
**Option A:** Fructose - While fructose is a reducing sugar, it is not typically associated with Congenital Hypoglycemia or the clinical presentation described.
**Option B:** Glucose - Glucose is not a reducing sugar and would not be detected by the Benedict's test.
**Option C:** Sucrose - Sucrose is a disaccharide composed of glucose and fructose, but it is not typically found in the urine of neonates with Congenital Hypoglycemia.
**Clinical Pearl / High-Yield Fact**
Neonates with Congenital Hypoglycemia often present with nonspecific symptoms, and the presence of reducing sugars in the urine can be a key diagnostic clue. Remember to consider this possibility in any neonate with unexplained hypoglycemia or metabolic derangements.
**Correct Answer: C. Galactose**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.