Paget’s disease of breast following are true except ?
**Core Concept**
Paget's disease of the breast is a rare form of breast cancer characterized by eczematous changes in the skin of the nipple and areola, often accompanied by underlying ductal carcinoma in situ (DCIS) or invasive breast cancer. This condition requires a comprehensive understanding of breast anatomy, pathology, and clinical presentation.
**Why the Correct Answer is Right**
Paget's disease of the breast typically presents with skin changes such as erythema, eczematous lesions, and sometimes, crusting or oozing. The condition is often associated with underlying breast cancer, particularly in the form of DCIS or invasive ductal carcinoma. The disease may also involve the underlying ducts, leading to nipple retraction or discharge. The clinical presentation of Paget's disease is often accompanied by a palpable mass, which can be a sign of underlying cancer.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as Paget's disease is not typically associated with lymphadenopathy. While lymph node involvement can occur in advanced cases of breast cancer, it is not a characteristic feature of Paget's disease.
**Option B:** This option is incorrect as Paget's disease is not a type of inflammatory breast cancer. While both conditions can present with skin changes, they have distinct pathological features and clinical presentations.
**Option C:** This option is incorrect as Paget's disease is not a type of fibroadenoma. Fibroadenomas are benign breast tumors that typically present as palpable masses, whereas Paget's disease is a form of breast cancer.
**Option D:** This option is incorrect as Paget's disease is not a type of galactocele. Galactoceles are milk-filled cysts that can occur in lactating women, whereas Paget's disease is a form of breast cancer.
**Clinical Pearl / High-Yield Fact**
A key clinical feature of Paget's disease is the presence of eczematous changes in the skin of the nipple and areola, often accompanied by a palpable mass or nipple retraction. This condition requires a high index of suspicion and prompt evaluation by a breast specialist.
**Correct Answer:** A.