A 12 year old girl with the mood and emotional liability has a golden brown discoloration in descement membrane. Most likely diagnosis is –
**Core Concept**
The question is testing the clinical presentation of a condition affecting the Descemet's membrane, which is a layer of the cornea. The golden brown discoloration is a characteristic feature of this condition, which is caused by the accumulation of a specific type of protein.
**Why the Correct Answer is Right**
The condition described is likely **Fuchs' heterochromic iridocyclitis**. This condition is characterized by chronic inflammation of the iris and ciliary body, leading to heterochromia (color difference) of the iris. The golden brown discoloration of the Descemet's membrane is due to the accumulation of lipofuscin, a type of waste material that accumulates in cells over time. The condition is often associated with mood and emotional changes, which may be related to the underlying inflammatory process.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not match the clinical presentation described in the question. Fuchs' heterochromic iridocyclitis is a specific condition that affects the iris and Descemet's membrane, and it is not characterized by the symptoms listed in this option.
**Option B:** This option is incorrect because it is not a specific diagnosis that matches the clinical presentation described in the question. While mood and emotional changes can be associated with various eye conditions, they are not a primary feature of this condition.
**Option C:** This option is incorrect because it is not a specific diagnosis that matches the clinical presentation described in the question. While heterochromia can be associated with various eye conditions, the golden brown discoloration of the Descemet's membrane is a specific feature of Fuchs' heterochromic iridocyclitis.
**Option D:** This option is incorrect because it is not a specific diagnosis that matches the clinical presentation described in the question. While mood and emotional changes can be associated with various eye conditions, they are not a primary feature of this condition.
**Clinical Pearl / High-Yield Fact**
Fuchs' heterochromic iridocyclitis is a chronic inflammatory condition that affects the iris and Descemet's membrane, leading to heterochromia and other ocular symptoms. It is often associated with mood and emotional changes, which may be related to the underlying inflammatory process.
**Correct Answer:** C.