**Core Concept**
Diethylstilbestrol (DES) is a synthetic estrogen that was historically prescribed to pregnant women to prevent miscarriage and other pregnancy complications. However, it has been linked to several reproductive tract abnormalities in offspring due to its **estrogenic effects** on fetal development.
**Why the Correct Answer is Right**
The correct answer is not provided, but the explanation will focus on the known effects of DES. DES exposure in utero has been associated with an increased risk of **clear cell adenocarcinoma of the vagina and cervix**, as well as other reproductive tract abnormalities such as **T-shaped uterus**, **hypoplastic uterus**, and **ovarian cysts**. The mechanism involves disruption of normal **hormone receptor** signaling pathways during critical periods of fetal development.
**Why Each Wrong Option is Incorrect**
**Option A:** Not provided, but would be incorrect if it described a known effect of DES.
**Option B:** Not provided, but would be incorrect if it described a known effect of DES.
**Option C:** Not provided, but would be incorrect if it described a known effect of DES.
**Option D:** Not provided, but would be incorrect if it described a known effect of DES.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that DES exposure is a significant risk factor for **clear cell adenocarcinoma of the vagina and cervix**, which is a rare but aggressive type of cancer.
**Correct Answer:** Not provided, as the question options are missing.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.