A 25 years old female with history of multiple contacts presents with growth on vulva, the probable diagnosis is –
**Core Concept:** Genital warts are caused by human papillomavirus (HPV) infection, which leads to the proliferation of keratinocytes and formation of warts. HPV can affect both men and women, and genital warts are more common in young adults due to high-risk HPV types acquired through sexual contact.
**Why the Correct Answer is Right:** In this question, the patient presents with a growth on the vulva, which is the most common site for genital warts. The correct answer is C. Vulvar warts, also known as condylomata acuminata, are caused by high-risk types of HPV. These high-risk types are transmitted sexually and are responsible for the development of cervical cancer. Since the patient has a history of multiple sexual contacts, it is more likely that she acquired the HPV infection through sexual contact, leading to vulvar warts.
**Why Each Wrong Option is Incorrect:** A) Vulvar leukoplakia is a thickening of the vulvar mucosa due to various causes like irritation, inflammation, or HPV infection. While it can be associated with HPV, it is less likely in a patient with a history of multiple sexual contacts. B) Vulvar carcinoma is a more advanced disease process than vulvar warts and is not directly caused by sexual contact. D) Vulvar lichen planus is a chronic inflammatory disorder affecting the skin and mucous membranes, which is not related to HPV infection or sexual contact.
**Clinical Pearl:** When examining patients with a history of multiple sexual contacts presenting with genital lesions, considering genital warts due to HPV infection is essential. Early diagnosis and treatment can prevent complications like cervical cancer. In these cases, counseling about safe sex practices and sexually transmitted infection (STI) prevention is crucial.