**Core Concept**
The question tests the clinical correlation between a specific skin finding (hypopigmented macules) and a neurological condition (seizures and developmental delay) in a young child. This scenario is suggestive of a neurocutaneous syndrome, where skin manifestations are associated with underlying neurological abnormalities.

**Why the Correct Answer is Right**
The presence of hypopigmented macules, particularly in a child with seizures and developmental delay, is highly suggestive of Tuberous Sclerosis Complex (TSC). TSC is a genetic disorder characterized by the growth of non-cancerous tumors in various parts of the body, including the skin, brain, and kidneys. The skin lesions, known as ash-leaf spots, are typically hypopigmented and oval in shape. In TSC, these lesions are due to the inactivation of the TSC1 or TSC2 gene, leading to the activation of the mammalian target of rapamycin (mTOR) pathway, which promotes cell growth and proliferation.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is likely a distractor related to another neurocutaneous syndrome, such as Neurofibromatosis Type 1 (NF1), which presents with cafe-au-lait macules, not hypopigmented macules.
**Option B:** This option might be a distractor related to a different neurological condition, such as Epilepsy, which can present with seizures but is not directly associated with the skin finding described.
**Option C:** This option could be a distractor related to a different genetic disorder, such as Sturge-Weber syndrome, which presents with port-wine stains, not hypopigmented macules.
**Option D:** This option is likely a distractor related to a different type of skin condition, such as Vitiligo, which presents with white patches but is not associated with seizures and developmental delay in a young child.

**Clinical Pearl / High-Yield Fact**
Tuberous Sclerosis Complex is a genetic disorder that affects multiple organ systems, and the presence of hypopigmented macules, along with seizures and developmental delay, is a classic triad that should raise suspicion for this condition. It's essential to consider TSC in the differential diagnosis of children with unexplained seizures and skin lesions.

**Correct Answer:** C.