Prior to ovulation, development of granules in the follicles is dependent on:-

**Core Concept**
The development of granules in the follicles is a critical step in the formation of the corpus luteum, which is essential for progesterone production and ovulation. This process is regulated by a complex interplay of hormones and enzymes.

**Why the Correct Answer is Right**
The correct answer is dependent on the enzyme aromatase, which is responsible for converting androgens into estrogens. Prior to ovulation, the follicles produce androgens, such as androstenedione, which are then converted to estrogens, like estradiol, by aromatase. This process promotes the growth and development of the follicles and the formation of granules, which eventually give rise to the corpus luteum. The increase in estrogen levels also stimulates the growth of the endometrium, preparing it for potential implantation of a fertilized egg.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not directly relate to the development of granules in the follicles. While LH (luteinizing hormone) plays a crucial role in ovulation, it is not directly involved in the formation of granules.

**Option B:** This option is incorrect because FSH (follicle-stimulating hormone) is primarily involved in the growth and development of the follicles, but it is not directly responsible for the formation of granules.

**Option C:** This option is incorrect because progesterone is a hormone produced by the corpus luteum, which forms after ovulation. It is not directly involved in the development of granules prior to ovulation.

**Clinical Pearl / High-Yield Fact**
Aromatase inhibitors are a class of medications that can be used to treat conditions like polycystic ovary syndrome (PCOS) by reducing estrogen levels. They work by inhibiting the action of aromatase, which is essential for estrogen production.

**Correct Answer:** C.