## Core Concept
Ovarian carcinoma is a type of cancer that affects the ovaries, and several risk factors have been identified for its development. These risk factors can be broadly categorized into genetic, hormonal, and lifestyle-related factors. Understanding these risk factors is crucial for early detection and prevention.
## Why the Correct Answer is Right
The correct answer, , is related to the fact that nulliparity (never having given birth) and early menarche/late menopause are known to increase the risk of ovarian cancer due to the increased number of ovulatory cycles, which may lead to genetic mutations in the ovarian epithelial cells. Family history of breast or ovarian cancer, particularly with mutations in the BRCA1 and BRCA2 genes, significantly increases the risk. On the other hand, pregnancy and breastfeeding have been shown to decrease the risk of ovarian cancer.
## Why Each Wrong Option is Incorrect
* **Option A:** is a known protective factor against ovarian cancer.
* **Option B:** can be related to hormonal factors and is a known risk factor.
* **Option C:** is indeed a risk factor, especially if there's a family history of breast or ovarian cancer.
## Why the Correct Answer is Right in Detail for D
* **Option D:** actually represents a protective factor or is not directly listed as a risk factor compared to the context of the question.
## Clinical Pearl / High-Yield Fact
A key clinical pearl is that the use of oral contraceptives can significantly reduce the risk of ovarian cancer, with the risk reduction increasing with the duration of use. This is a high-yield fact for exams.
## Correct Answer Line
**Correct Answer: D. oral contraceptive use.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.