**Core Concept**
Desmopressin is a synthetic analogue of vasopressin, which is used to manage various conditions related to its antidiuretic and vasoconstrictive properties. It is a selective V2 receptor agonist, which helps in reducing urine output and increasing water reabsorption in the kidneys.
**Why the Correct Answer is Right**
Desmopressin is used to treat conditions such as nocturnal enuresis (bedwetting), diabetes insipidus, and hemophilia A and B. It works by increasing the permeability of the collecting ducts in the kidneys to water, thereby reducing urine output. Desmopressin is also used to manage bleeding episodes in patients with hemophilia A and B due to its ability to increase the levels of factor VIII and factor IX in the blood.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because desmopressin is not used to treat hypertension. In fact, its vasoconstrictive properties can potentially worsen hypertension.
**Option B:** This option is incorrect because desmopressin is not used to treat conditions related to the parathyroid gland. It does not have any significant effects on calcium levels or parathyroid hormone secretion.
**Option C:** This option is incorrect because desmopressin is not used to treat conditions related to the thyroid gland. It does not have any significant effects on thyroid hormone levels or thyroid function.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that desmopressin should not be used in patients with cardiac disease, as it can cause fluid overload and hypertension. Additionally, patients with diabetes mellitus should be monitored closely for signs of fluid overload and hyponatremia when taking desmopressin.
**Correct Answer:** A.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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